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However, an important issue concerns the details of the mode of delivery of steroid hormones to their target cells, anabol 5 para que serve. Since the 'free' form of the steroid hormone is believed to be the form of steroid that moves across the outer plasma membrane of a target cell, it had been postulated that the steroid ligand bound to a plasma transport protein dissociates from its plasma transport protein and then diffuses first through the capillary wall and then through the outer wall membrane of target cells. However, as illustrated in Figure 2-23 it is apparent that the endothelial wall of capillaries contains fenestrations. Thus, it is also possible for the plasma steroid transport protein (with bound steroid horone) to exit the capillary bed via a fenestration and move to be immediately adjacent to the outer cell membrane of the appropriate target cell for the steroid hormone in question. Here the steroid hormone will dissociate from the transport protein, diffuse through the plasma membrane, and then bind to an unoccupied partner steroid receptor.
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